Human cytomegalovirus UL102 gene

Human Cytomegalovirus: Infections and Diagnosis

Human cytomegalovirus (HCMV) is a ubiquitous virus whose sole host is humans. Since HCMV can contagion from person to person through numerous ways, vast populations of humans are infected. HCMV infections can potentially have a range from asymptomatic infection in immuno-competent hosts to life-threatening diseases in organ recipients and patients with AIDS. The present article reviews the occu...

Characterization of the human cytomegalovirus UL34 gene.

UL34 encodes the transcriptional repressor of the human cytomegalovirus immune evasion gene, US3, and is essential for viral replication in tissue culture. Two different monocistronic transcripts originate from UL34 at early and late times postinfection and encode two predominant proteins and a third, minor protein. The UL34 proteins are differentially expressed throughout the viral replication...

Analysis of human cytomegalovirus US3 gene products.

Similar to other herpesviruses, human cytomegalovirus remains in the infected host following resolution of the primary infection. The ability to persist in the host after primary infection is believed to be strongly influenced by the ability of HCMV to down-regulate immune recognition of infected cells. One of the genes contributing to immune evasion is the US3 gene. The US3 gene has been shown...

Expression Monocytes Induces Immunoregulatory Gene Human Cytomegalovirus Binding to Human

Monocytes Induces Immunoregulatory Gene Human Cytomegalovirus Binding to Human